Biology Research Scientist<br><br><strong>Job Type:</strong> Contractor<br><br><strong>Location:</strong> Remote<br><br><strong>Hours:</strong> 10-20 hours/week<br><br><strong>Duration:</strong> 1-2 months minimum, with likely extension<br><br><strong>Start:</strong> Immediate<br><br><strong>Job Overview<br><br></strong>We are seeking experienced <strong>Biology Research Scientists</strong> to support a project focused on validating protein target assignments against primary scientific sources and UniProt records.<br><br>You will review research papers and patents, identify target assignment errors, propose corrected UniProt accessions, and provide concise, evidence-based scientific reasoning.<br><br>Key Responsibilities<br><br><ul><li>Review primary research papers and patents to verify protein target assignments. </li><li>Compare target assignments against UniProt and identify discrepancies. </li><li>Classify target assignment errors using a structured taxonomy. </li><li>Propose accurate UniProt accessions where assignments are incorrect. </li><li>Document clear, concise, evidence-grounded reasoning for each determination. </li><li>Apply expertise in pharmacology, biochemistry, molecular biology, or chemical biology to evaluate target relationships. <br><br></li></ul><strong>Required Skills<br><br></strong><ul><li>Protein Target Identification </li><li>UniProt </li><li>Primary Literature Review </li><li>Protein Biochemistry </li><li>Molecular Biology </li><li>Pharmacology </li><li>Binding & Functional Assays </li><li>Scientific Data Interpretation </li><li>Evidence-Based Reasoning </li><li>Technical Documentation <br><br></li></ul><strong>Qualifications<br><br></strong><ul><li>BA/BS + 5 years, MS + 2 years, or PhD with relevant industry/drug discovery experience. </li><li>Background in pharmacology, biochemistry, molecular biology, or chemical biology within biotech, pharma, or CRO environments. </li><li>Hands-on experience with assays such as SPR, TR-FRET, radioligand binding, kinase assays, or GPCR functional assays. </li><li>Experience interpreting IC50, Ki, and Kd data. </li><li>Currently active in a bench-based research, scientist, or associate scientist role. </li><li>Working knowledge of UniProt or related workflows such as SAR, HTS, target validation, biochemical profiling, or IND-enabling studies. <br><br></li></ul>Nice to Have<br><br><ul><li>Experience with ChEMBL, BindingDB, or PubChem. </li><li>Selectivity profiling or counterscreening experience. </li><li>Understanding of agonist/antagonist vs. activator/inhibitor distinctions. <br><br></li></ul>Screening Questions<br><br><ul><li>What is your highest relevant degree and how many years of industry research experience do you have? </li><li>What is your experience with protein target identification and UniProt? </li><li>Which binding or functional assays have you performed hands-on? </li><li>Do you have experience interpreting IC50, Ki, or Kd data? </li><li>Have you worked with ChEMBL, BindingDB, or PubChem? </li><li>Are you currently bench-active in a research or scientist role? </li><li>Are you available for 10-20 hours per week with an immediate start?</li></ul>